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Generation of porcine transgenic cell line targeting heart-specific gene expression for xenotransplantation
target genes in the proposed transgenic pigs to provide an excellent source of immuno-compatible heart ... Administration of the Republic of Korea Description: The primary impact of this project will be the ... identification of a new set of heart specific genes in pigs and use of their promoters for the expression of ...
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Kichoon Lee
https://ansci.osu.edu/our-people/kichoon-lee
Generation of Transgenic Quail Expressing GFP in Gut Epithelial Cells. International Journal of Molecular ... Hwang S, Lee C, Lee K. 2017. Targeted genome editing in a quail cell line using a customized CRISPR/Cas9 ... 2022. Generation of genome-edited chicken and duck lines by adenovirus-mediated in vivo genome editing. ...
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Agrobacterium
https://rbil.osu.edu/research/agrobacterium
the invading bacteria to a cell of an infected host plant. The T-DNA is then integrated stably into ... the chromosome of the infected plant cell and the genes located on the T-DNA are expressed causing ... rapid reorganization and division of the cell to form tumor-like structures (A. tumefaciens or A. vitis) ...
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Porcine Rotaviruses
https://viroimmunelab.osu.edu/publications/porcine-rotaviruses
(pararotavirus) in a continuous cell line and characterization of the passaged virus. J Clin Microbiol 26:1277-82. ... 1987. Serial propagation of porcine group C rotavirus (pararotavirus) in primary porcine kidney cell ... porcine rotavirus in porcine kidney cell cultures and intestinal epithelial cells. J Gen Virol 39:205-17. ...
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OARDC scientists working to fight new deadly U.S. swine disease
spread of porcine epidemic diarrhea virus (PEDV), a disease of swine that was found for the first time ... six-month project that involves growing the virus in the lab and using this material to develop ... Saif, an international expert on viral diseases of swine and cattle and a Distinguished University ...
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Porcine, Bovine and Human Enteric Calicivirus
https://viroimmunelab.osu.edu/publications/porcine-bovine-and-human-enteric-calicivirus
1991. Serial propagation of porcine enteric calicivirus in a continuous cell line. Effect of medium ... L.J. Saif. 2002. Cell-culture propagation of porcine enteric calicivirus mediated by intestinal ... porcine enteric calicivirus-like virus in primary porcine kidney cell cultures. J Clin Microbiol ...
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Scott Kenney, PhD
https://cfah.osu.edu/people/scott-kenney-phd
viruses, Hepatitis E virus, PRRSV, Porcine delta coronavirus, SARS-CoV-2 Food Animal Health Building, CFAES ... (HEV), porcine deltacoronavirus (PDCoV), African swine fever virus, and turkey reovirus. We have ... of acute viral hepatitis worldwide. HEV is endemic to developing countries where poor sanitation ...
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Kichoon Lee Awarded Two USDA Grants
https://ansci.osu.edu/news/kichoon-lee-awarded-two-usda-grants
of a strategy to directly target more germ cells by injecting the CRISPR/Cas9 adenovirus into the ... a total budget of $500,000 for 2 years. The titles of the two projects are “Characterization of ... poultry”. Both projects started on June 01, 2020. The Non-Technical Summaries of the two projects are below. ...
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Qiuhong Wang, BM, MS, PhD
https://cfah.osu.edu/people/qiuhong-wang-bm-ms-phd
Food Safety Cell Culture Adaptation of Enteric Viruses Interspecies Transmission Coronaviruses [porcine ... Epidemic Diarrhea Virus (PEDV), porcine deltacoronavirus, severe acute respiratory syndrome-coronavirus-2 ... molecular epidemiology, adaptation of enteric viruses in cell culture, mechanisms of virus attenuation, ...
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Anastasia Vlasova, DVM, PhD
https://cfah.osu.edu/people/anastasia-vlasova-dvm-phd
diarrhea and mortality worldwide and an important pathogen in young animals; CoVs represent a continuous ... public health threat evidenced by recent trans- boundary spread and pandemics of animal (porcine epidemic ... pig model demonstrated that coordinate involvement of different innate immune cells is critical to ...